This episode is a conversation with NASA “space doctor” Jim Logan about space medicine and telemedicine. We start by defining the two concepts and how they relate. We then delve deeper into various specific medical issues in space (such as fluid shifts, bone mass loss and radiation). Next up is a discussion of the history of telemedicine and its relationship to space medicine, which leads us to looking astronauts can be treated for “normal” diseases from ground. We concluse the episode with an outlook on how telemedicine might develop in the future.